October 15, 2025

Acute Phase Reactants and Hematologic Profiles vs Blood Culture in Late Preterm Neonatal Sepsis

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Cross-sectional analysis evaluates blood culture against acute phase reactants in late preterm infants, suggesting enhanced diagnostic accuracy.

CRP positivity was found in 91.4% of neonates, demonstrating its potential as a diagnostic marker in sepsis.
Blood culture, the gold standard, was positive in 25.7% of cases, highlighting its importance despite antibiotic interference.
Late-onset sepsis affected 60% of the study population, emphasizing the need for effective early detection strategies.
Abnormal white blood cell counts were noted in 64.3% of cases, suggesting hematologic profiles contribute valuable diagnostic information.

Naji et al. (2025) studied this question.

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Cross-sectional analysis evaluates blood culture against acute phase reactants in late preterm infants, suggesting enhanced diagnostic accuracy.