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October 15, 2025Frontiers in EndocrinologyOpen Access

Mechanisms of microbial infection and wound healing in diabetic foot ulcer: pathogenicity in the inflammatory-proliferative phase, chronicity, and treatment strategies

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Authors

QWQi WangCLChuyu LiuJAJing An

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Overview

This review explores microbial infections and healing dynamics in diabetic foot ulcers, suggesting management strategies.

Key Points

  • Microbial infection significantly disrupts wound healing in diabetic foot ulcers, contributing to chronicity.
  • Diabetic foot infections can lead to severe complications, including non-healing wounds and possible amputation.
  • Current treatment strategies for diabetic foot ulcers must address both microbial factors and healing processes.
  • Understanding pathogenic mechanisms offers new insights into improving clinical management of diabetic foot ulcers.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68efd921056559ef4287760bhttps://doi.org/10.3389/fendo.2025.1657928
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