October 15, 2025Scientific ReportsOpen Access

A pilot experimental study of cold-chain management, haemolysis and oxidative stress of packed red blood cells in early blood transfusion: toward a blood viability model in the out-of-hospital setting

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Packed red blood cells transported in ambulances showed haemolysis levels below the critical threshold after 35 days.
The treatment group maintained temperature within the 1–10°C range, demonstrating effective cold-chain management.
Statistical analysis confirmed no significant oxidative stress or cellular degradation in the transported blood samples.
Findings suggest potential for improved blood transfusion practices in low- and middle-income countries.

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Experimental study demonstrates blood viability in packed red blood cells on ambulances, indicating effective cold-chain management.

Zeenat et al. (2025) studied this question.

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