October 13, 2025

[Update of pathology in medullary thyroid carcinoma].

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Medullary thyroid carcinoma (MTC) presents diverse histological patterns, and its classification affects treatment decisions.
Most cases of MTC stem from mutations in the RET gene, highlighting the importance of genetic screening for risk assessment.
The updated WHO classification distinguishes MTC into low-grade and high-grade, serving as prognostic indicators for recurrence.
Immunohistochemical staining reveals variable expression of neuroendocrine markers, impacting diagnosis and treatment strategies.

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Implication

This update reports on histological grading and RET gene mutations in medullary thyroid carcinoma, indicating implications for recurrence and targeted therapy.

Cite This Study

Yu et al. (2025) studied this question.

synapsesocial.com/papers/68ece2abd1bb2827d1297378 https://doi.org/10.3760/cma.j.cn112151-20250128-00067

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Implication

This update reports on histological grading and RET gene mutations in medullary thyroid carcinoma, indicating implications for recurrence and targeted therapy.

[Update of pathology in medullary thyroid carcinoma].

Key Points

Discussion

Implication

Cite This Study

[Update of pathology in medullary thyroid carcinoma].

Key Points

Discussion

Implication

Cite This Study

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