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October 13, 2025Russian Journal of CardiologyOpen Access

Long-term prognosis in patients with heart failure with reduced left ventricular ejection fraction, atrial fibrillation and implanted cardiac contractility modulation devices

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Authors

АСА. А. СафиуллинаTUT. M. UskachСТС. Н. Терещенко

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Overview

Analysis shows reduced cardiovascular death in heart failure patients with atrial fibrillation using cardiac contractility modulation devices, indicating improved survival rates.

Key Points

  • CCM therapy significantly lowers cardiovascular death rates in heart failure patients with atrial fibrillation.
  • 24% of patients in the CCM group died compared to 46% in the optimal therapy group, underlining the potential benefits of CCM.
  • Primary endpoint results indicate 38% cardiovascular death in the optimal therapy group versus 19% in the CCM group over 5 years.
  • CCM therapy also reduces all-cause death risk, with significant differences noted in long-term follow-up.

Cite This Study

Сафиуллина et al. (2025) studied this question.

synapsesocial.com/papers/68ec51df42911f61ef8b22e4https://doi.org/10.15829/1560-4071-2025-6093
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