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October 13, 2025The Journal of Clinical PharmacologyOpen Access

Post‐Marketing Safety Assessment for Glucagon‐Like Peptide‐1 and Dual Incretin Therapies in Diabetes and Obesity

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Authors

CWChien‐Hsiang WengCBCharles L. BennettJMJoseph Magagnoli

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Overview

Observational analysis highlights potential adverse drug reactions in patients receiving GLP-1RAs and tirzepatide, indicating a need for careful pharmacovigilance.

Key Points

  • Accurate interpretation of potential adverse drug reactions is essential for clinicians to counsel patients effectively.
  • Pharmacovigilance efforts show significant disparities in reporting practices between healthcare professionals and patients.
  • Tirzepatide's unique mechanism may lead to different side effects, underscoring the need for drug-specific analyses.
  • Long-term post-marketing surveillance is crucial to identify rare adverse events associated with newer therapies.

Cite This Study

Weng et al. (2025) studied this question.

synapsesocial.com/papers/68ec51df42911f61ef8b20eehttps://doi.org/10.1002/jcph.70119
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