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October 12, 2025Clinical and Translational ScienceOpen Access

Real‐World Characterization of Psychiatric Pharmacogenomic Test Ordering and Clinical Relevance in Adults and Children

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Authors

LZLusi ZhangATAnthony J. TholkesUniversity of MinnesotaKJKevin Jones

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Implication

Analysis shows patterns of pharmacogenomic testing in adults and children, suggesting significant clinical implications.

Key Points

  • Ninety-four point five percent of individuals had actionable pharmacogenomic variants, indicating high clinical relevance.
  • Drug-gene interactions were identified for current medications in 19.3% of adults and 15.0% of youth, showing the importance of testing.
  • Barriers include inconsistent integration of pharmacogenomic results into electronic health records, limiting their utility in practice.
  • Disparities in test ordering correlated with gender and race, highlighting systemic inequities and variability in provider practices.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68ec1be02b8fa9b2b78ad351https://doi.org/10.1111/cts.70297
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