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October 12, 2025Reviews in Cardiovascular MedicineOpen Access

Antiplatelet Therapy in Chronic Coronary Artery Disease Patients With a History of Angioplasty. When is Aspirin Not Enough? A Systematic Review

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Authors

SFStylianos FiflisMPMichail PapamichalisΑXΑndrew Xanthopoulos

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Overview

Systematic review highlights antiplatelet therapy impact on thrombotic risks in coronary patients, suggesting individualized treatment strategies.

Key Points

  • Extended dual antiplatelet therapy showed improved outcomes compared to aspirin alone in coronary disease patients.
  • Long-term clopidogrel monotherapy was effective, yielding better primary outcomes and reducing major bleeding risks.
  • Subgroup analyses revealed significant benefits of extended therapy in those with prior myocardial infarction and peripheral artery disease.
  • Individualized treatments based on thrombotic and bleeding risks are crucial for optimal patient outcomes in coronary syndrome.

Cite This Study

Fiflis et al. (2025) studied this question.

synapsesocial.com/papers/68ec1be02b8fa9b2b78ad050https://doi.org/10.31083/rcm44227
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