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October 12, 2025Scientific ReportsOpen Access

Impact of selenium status and supplementation on outcomes in critically ill patients

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Authors

HTHongwei TanYLYingkuan LiangYSY M Shao

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Implication

Observational study links serum selenium levels and supplementation to lower ICU mortality in patients.

Key Points

  • Adequate selenium repletion is linked to significantly lower ICU mortality among critically ill patients.
  • About 27.8% of ICU patients had selenium levels below 70 µg/L, correlated with higher severity scores.
  • Observational study evaluated 144 ICU patients, measuring serum selenium and analyzing clinical outcomes.
  • Lower selenium levels indicate greater illness severity and impact clinical outcomes, suggesting the need for supplementation.

Cite This Study

Tan et al. (2025) studied this question.

synapsesocial.com/papers/68ebc91af2c3e4d8d926e1d3https://doi.org/10.1038/s41598-025-19315-w
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