Experimental evaluation shows Justicia carnea restores liver and kidney functions in mice with immunotoxicity induced by sheep red blood cells, indicating its potential as an adjuvant.
Key Points
Justicia carnea significantly improves liver and kidney functions in mice following SRBC-induced immunotoxicity.
Levels of AST, ALT, ALP, and ALB were significantly altered in SRBC mice, indicating liver stress with almost full recovery observed post-treatment.
Mice receiving 250 and 500 mg/kg of Justicia carnea had significantly increased total protein levels compared to control groups.
Aqueous extract treatment reduced SRBC-induced urea concentration, yet levels did not revert entirely to baseline, highlighting its protective impact.