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October 11, 2025Tropical Journal of Pharmaceutical ResearchOpen Access

Antiplasmodial and antitrypanosomal effects of some plant extracts utilized within Nigerian traditional healing practices

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Authors

IOIjeoma S. OkoroSUSampson D. UmohAAAnita K. Asekunowo

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Overview

Observational analysis reveals strong antiplasmodial and antitrypanosomal properties in plant extracts, indicating potential for traditional medicine.

Key Points

  • Extracts of A. djalonensis and P. angolensis significantly reduced the viability of P. falciparum and T. brucei.
  • The IC50 values for A. djalonensis, V. cinerea, and P. angolensis were found to be 0.0036, 2.818, and 4.677 μg/mL, respectively.
  • Plant extracts were tested against 10⁶ – 10⁷ parasites/mL for T. brucei and various parasitemia levels for P. falciparum.
  • A. djalonensis and P. angolensis show potential for further investigation as sources for antiplasmodial and antitrypanosomal agents.

Cite This Study

Okoro et al. (2025) studied this question.

synapsesocial.com/papers/68e9b1d9ba7d64b6fc132f4ehttps://doi.org/10.4314/tjpr.v24i5.8
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