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October 11, 2025AntioxidantsOpen Access

Screening of Mediterranean Plant-Derived Extracts for Antioxidant Effect in Cell-Free and Human Cell Line Models

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Authors

GAGiuseppe ArgentinoELEdoardo Giuseppe Di LeoCSChiara Stranieri

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Overview

Systematic screening reveals the antioxidant potential of various plant-derived extracts, highlighting their role in modulating oxidative stress.

Key Points

  • Strong antioxidant activities were observed in extracts like Acalypha virginica and Actinidia deliciosa.
  • Fifteen extracts significantly reduced reactive oxygen species levels in human THP-1 cells without causing cytotoxicity.
  • Higher extract concentrations resulted in apoptosis or necrosis, indicating the need for careful dosage definitions.
  • This analysis suggests potential therapeutic applications of Mediterranean plant extracts for oxidative stress-related disorders.

Cite This Study

Argentino et al. (2025) studied this question.

synapsesocial.com/papers/68e9b1d0ba7d64b6fc132c15https://doi.org/10.3390/antiox14101217
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