This experimental study shows nanoemulsion of curcuma longa improves body length and reduces ocular apoptosis in zebrafish, indicating potential therapeutic benefits.
Key Points
A nanoemulsion of curcuma longa extract improved body length in high glucose-exposed zebrafish embryos, enhancing their development.
1.25 µg/mL of the nanoemulsion reduced PEPCK expression and ocular apoptosis, suggesting an antioxidant effect.
Using the self-nanoemulsifying drug delivery system, embryos were treated across five groups to assess developmental impacts.
These findings highlight the potential for using curcuma longa to mitigate hyperglycemia's harmful effects on fetal development.