Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 10, 2025Journal of Experimental & Clinical Cancer ResearchOpen Access

The cGAS‒STING pathway in colorectal cancer: bridging innate immunity and therapeutic strategies

View Full Paper
Ask AI
Bookmark
Share

Authors

WLWenjing LiGDGuang‐Hui DongYBYao Bi

Discussion

Loading...

Member takes

Overview

Review highlights the cGAS-STING pathway's dual role in CRC and its implications for immunotherapy strategies.

Key Points

  • The cGAS-STING pathway triggers immune responses while promoting inflammation in colorectal cancer.
  • Recent studies indicate that targeting this pathway could improve immunotherapy's efficacy against CRC.
  • Nanotechnology advancements enable accurate delivery of STING agonists, enhancing therapeutic outcomes in CRC.
  • Understanding cGAS-STING's roles in colorectal cancer may inform future strategies for effective immunotherapy.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68e861b07ef2f04ca37e4960https://doi.org/10.1186/s13046-025-03544-y
View Full Paper
Ask AI
Bookmark
Share