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October 10, 2025Open Access

Evaluation of liver function in patients with cirrhosis based on dual-energy CT imaging combined with serum fibrosis markers：a feasibility study

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Authors

ZWZhenhua WangZDZhijun DaiYZYongqi Zhu

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Overview

Prospective study finds dual-energy CT imaging combined with serum fibrosis markers improves cirrhosis evaluation.

Key Points

  • The test indicates that fECV is a reliable imaging index for diagnosing cirrhosis.
  • Among indicators, fECV demonstrated the highest AUC of 0.818 for cirrhosis diagnosis.
  • ROC analysis and logistic regression helped identify independent risk factors for cirrhosis.
  • The predictive model enhanced diagnostic accuracy for assessing Child-Pugh grades significantly.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68e861a57ef2f04ca37e467chttps://doi.org/10.21203/rs.3.rs-7141662/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dual Energy CT-Derived Liver Extracellular Volume Fraction for Assessing Liver Functional Reserve in Patients with Liver Cirrhosis2025 · 1 citations
  2. 2Multiparametric Dual-Energy CT for ALBI-Based Liver Function Stratification in Cirrhosis: Diagnostic Accuracy and Clinical Utility2025
  3. 3Predicting Chronic Liver Disease Severity by Liver and Splenic Extracellular Volume Fraction Derived from spectral-CT2025
  4. 4Comparison of Noninvasive Methods for the Evaluation of Liver Fibrosis in Children With Chronic Hepatitis C Virus Infection2025
  5. 5The Value of Combinational Elastography in Assessing Fibrosis Staging in Patients with Liver Fibrosis in Chronic Liver Disease2025