October 10, 2025Journal of Heterocyclic Chemistry

Synthesis of Naphtho2,3‐b1,10phenanthrolines and Benzo6,7chromeno3,2‐fquinolines: One‐Pot Three‐Component Reaction of 2‐Hydroxy‐1,4‐Naphthoquinone, Aryl Aldehydes, and 8‐Aminoquinoline or 6‐Hydroxyquinoline

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Authors

MAMohaddeseh Ahmadusefi‐Sarhadi HMHossein Mehrabi FAFarzaneh Alizadeh‐Bami

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Implication

This one-pot three-component reaction synthesizes naphtho[2,3-b][1,10]phenanthrolines and benzo[6,7]chromeno[3,2-f]quinolines, highlighting molecular versatility.

Key Points

The synthesis yields new polycyclic compounds, enhancing the library of fused heterocycles.
Using a one-pot reaction simplifies the process, yielding products in high purity and operational efficiency.
The method employs tandem Knoevenagel and Michael reactions, demonstrating robust reaction pathways.
Spectroscopic techniques confirm the structure and purity of synthesized phenanthrolines and quinolines.

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Ahmadusefi‐Sarhadi et al. (2025) studied this question.

synapsesocial.com/papers/68e8619c7ef2f04ca37e4275 https://doi.org/10.1002/jhet.70105

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Implication

This one-pot three-component reaction synthesizes naphtho[2,3-b][1,10]phenanthrolines and benzo[6,7]chromeno[3,2-f]quinolines, highlighting molecular versatility.

Synthesis of Naphtho2,3‐b1,10phenanthrolines and Benzo6,7chromeno3,2‐fquinolines: One‐Pot Three‐Component Reaction of 2‐Hydroxy‐1,4‐Naphthoquinone, Aryl Aldehydes, and 8‐Aminoquinoline or 6‐Hydroxyquinoline

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Synthesis of Naphtho2,3‐b1,10phenanthrolines and Benzo6,7chromeno3,2‐fquinolines: One‐Pot Three‐Component Reaction of 2‐Hydroxy‐1,4‐Naphthoquinone, Aryl Aldehydes, and 8‐Aminoquinoline or 6‐Hydroxyquinoline

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