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October 10, 2025Frontiers in MedicineOpen Access

Machine learning-based mortality risk prediction models in patients with sepsis-associated acute kidney injury: a systematic review

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Authors

XLXu LiXHXu HuHXHuiting Xu

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Overview

Systematic review evaluates mortality risk prediction models for sepsis-associated acute kidney injury, highlighting model validation and methodological rigor.

Key Points

  • Machine learning models provide reliable mortality predictions for patients with sepsis-associated acute kidney injury, but biases exist.
  • Nine studies were analyzed, with commonly used methods including extreme gradient boosting, showing high area under the curve values.
  • The comprehensive assessment of existing prediction models indicated the need for standardized processes in feature selection and validation.
  • Future research should prioritize interpretability alongside robust model construction to ensure successful healthcare integration.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68e861907ef2f04ca37e3e03https://doi.org/10.3389/fmed.2025.1680180
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