Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 9, 2025

A Prognostic Risk Signature Based on Myeloid-Derived Suppressor Cells and Regulatory T Cells in Clear Cell Renal Cell Carcinoma.

View Full Paper
Ask AI
Bookmark
Share

Authors

ZXZhaoyu XuKLKen LiuQXQiangqiang Xu

Discussion

Loading...

Member takes

Overview

Immune infiltration analysis identifies prognostic markers in clear cell renal cell carcinoma, suggesting clinical relevance.

Key Points

  • A risk signature based on myeloid-derived suppressor cells and regulatory T cells predicts clinical outcomes.
  • The signature indicates higher risk scores correlate with advanced clinical subgroups and poorer immunotherapy response.
  • Machine learning methods identified differentially expressed genes related to myeloid-derived suppressor cells and regulatory T cells.
  • Independent validation across GEO datasets supports the signature's prognostic capability in clear cell renal cell carcinoma.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68e80eb363e2e2f707877b57https://doi.org/10.1177/15330338251382839
View Full Paper
Ask AI
Bookmark
Share