October 9, 2025Hypertension

Life-Course Burden of Blood Pressure Is Associated With Midlife Cognitive Function

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Higher cumulative blood pressure throughout life is linked to lower cognitive function at midlife.
Midlife cognitive function correlates negatively with total and incremental AUCs of systolic blood pressure.
This analysis involved 912 participants from the Bogalusa Heart Study, tracking cardiovascular risk factors over decades.
Long-term trajectories of blood pressure provide better risk assessment for cognitive decline than single measures.

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Longitudinal analysis reveals blood pressure trajectories impact midlife cognitive function, highlighting risk factors.

Chen et al. (2025) studied this question.

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