The cost of migraine to the NHS in England: a retrospective cohort study using electronic health record data from Clinical Practice Research Datalink (CPRD) and Hospital Episode Statistics (HES)

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Patients diagnosed with migraine incur about 81% greater direct medical costs annually compared to controls.
In a cohort of 62,143 migraine cases, median annual costs were £492, contrasting with £272 for matched controls.
Data was collected from linked primary and secondary healthcare sources, including Clinical Practice Research Datalink and Hospital Episode Statistics.
Findings imply that migraine management strategies need improvement to alleviate costs associated with secondary care.

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Retrospective cohort study shows significantly higher direct medical costs for migraine patients in England, indicating healthcare burden.

Collings et al. (2025) studied this question.

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Retrospective cohort study shows significantly higher direct medical costs for migraine patients in England, indicating healthcare burden.