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October 9, 2025Advanced ScienceOpen Access

Cancer: From a Genetic Disorder to a Systemic Disease

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Authors

AWAda Hang‐Heng WongYHYuming Hu

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Overview

Analysis indicates systemic disease patterns in cancer, highlighting tumor microenvironment and epigenetic factors for advanced treatments.

Key Points

  • Cancer is recognized as a systemic disease influenced heavily by its tumor microenvironment and genetics, rather than merely a genetic disorder.
  • Key evidence shows significant interactions between cancer genetics and tumor macroenvironment, paving the way for future therapeutic strategies.
  • Observational analysis emphasizes the necessity for translational research to address the complex dynamics of oncogenes and tumor suppressor genes.
  • This evolving perception highlights a need for multidisciplinary collaboration to advance understanding of cancer treatment and patient care.

Cite This Study

Wong et al. (2025) studied this question.

synapsesocial.com/papers/68e7d631bd66d359be62660bhttps://doi.org/10.1002/advs.202518885
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