Clinical improvement of salt-and-pepper skin changes in juvenile systemic sclerosis using mycophenolate mofetil after intravenous methylprednisolone: a 3-year follow-up
Case report shows resolution of salt-and-pepper skin changes in juvenile systemic sclerosis using mycophenolate mofetil, indicating potential anti-fibrotic benefits.
Key Points
The modified Rodnan skin score improved from 25 to 0, demonstrating effective treatment in juvenile systemic sclerosis.
Intravenous methylprednisolone followed by mycophenolate mofetil demonstrated beneficial effects on skin changes in a 12-year-old patient.
This case is the first report documenting improvement of salt-and-pepper skin changes in juvenile systemic sclerosis after specific treatment.
Recognition of salt-and-pepper changes may prompt earlier diagnosis and intervention in juvenile systemic sclerosis cases.