October 9, 2025Scientific ReportsOpen Access

Enhancing prognostic accuracy in PMBCL: semiquantitative analysis of interim PET/CT scans

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Authors

VHVeronika HanáčkováUniversity Hospital Olomouc KPKamila PolgárováCharles University LHLenka HenzlováUniversity Hospital Olomouc

Discussion

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Implication

Retrospective analysis shows event-free survival differences in PMBCL based on interim PET/CT metrics, suggesting radiomics enhances predictive accuracy.

Key Points

Event-free survival at 3 years was significantly higher in iPET-negative patients than in iPET-positive patients.
Among patients with high-quality iPET/CT, dSUVmax, dMTV, and dTLG metrics provided superior predictive accuracy for outcomes.
The study reviewed interim PET/CT scans from 116 PMBCL patients treated with anthracycline-based therapies.
Incorporating radiomics metrics could improve patient risk stratification and personalize treatment strategies.

Cite This Study

Hanáčková et al. (2025) studied this question.

synapsesocial.com/papers/68e7ba40ccde5f1021f649ef https://doi.org/10.1038/s41598-025-18649-9

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Implication

Retrospective analysis shows event-free survival differences in PMBCL based on interim PET/CT metrics, suggesting radiomics enhances predictive accuracy.