Safety and tolerance of infant formulas containing probiotics: a multicenter, randomised, controlled trial in healthy term infants

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Randomised controlled trial finds non-inferior growth in infants fed with probiotics, indicating their safety and tolerance.

Weight gain in infants fed probiotics was non-inferior compared to those without, showcasing effective growth across groups.
Mean weight gain for L. reuteri was −0.378 g/day, while B. lactis was −1.724 g/day, both under the non-inferiority margin.
The study involved 256 infants with no adverse events reported, ensuring both probiotic formulas were well-tolerated.
Fecal lactobacilli counts significantly increased with L. reuteri, suggesting enhanced digestive health in probiotic-fed infants.

Mitra et al. (2025) studied this question.

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View Full Paper

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Authors

Randomised controlled trial finds non-inferior growth in infants fed with probiotics, indicating their safety and tolerance.

Weight gain in infants fed probiotics was non-inferior compared to those without, showcasing effective growth across groups.
Mean weight gain for L. reuteri was −0.378 g/day, while B. lactis was −1.724 g/day, both under the non-inferiority margin.
The study involved 256 infants with no adverse events reported, ensuring both probiotic formulas were well-tolerated.
Fecal lactobacilli counts significantly increased with L. reuteri, suggesting enhanced digestive health in probiotic-fed infants.

Mitra et al. (2025) studied this question.

View Full Paper

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Bookmark