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October 9, 2025Vascular and Endovascular Surgery

Association Between Life’s Essential 8 Score and Stroke Risk in American Adults

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Authors

JTJiacong TanHZHuaxin ZhuYZYanyang Zeng

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Overview

Observational analysis found lower stroke risk linked to higher Life's Essential 8 scores in American adults, indicating cardiovascular health plays a vital role.

Key Points

  • A total of 31,653 subjects were analyzed, with 1187 (3.8%) experiencing a stroke.
  • Subjects with intermediate cardiovascular health had a lower stroke risk (OR = 0.5), while high levels further reduced risk (OR = 0.29).
  • Multivariate logistic regression and propensity score matching were employed to analyze the correlation between LE8 scores and stroke risk.
  • The findings suggest that increased Life's Essential 8 scores can significantly lower stroke risk, underscoring the need for early screening and targeted interventions.

Cite This Study

Tan et al. (2025) studied this question.

synapsesocial.com/papers/68e70da790569dd607ee5c76https://doi.org/10.1177/15385744251387784
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Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Defining and Setting National Goals for Cardiovascular Health Promotion and Disease Reduction2010 · 4,836 citations