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October 9, 2025Moldovan Journal of Health Sciences

Tuberculosis in new cases: the impact of HIV status on clinical manifestations

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Authors

IIIgor IvanesAUAurelia UstianCIConstantin Iavorschi

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Overview

Retrospective study reveals HIV co-infection increases severity and complication rates in tuberculosis patients.

Key Points

  • Patients with HIV co-infection showed significantly higher rates of generalized tuberculosis, reaching 28.8%.
  • Mortality rates were markedly higher among HIV-positive individuals, with 28.1% compared to 6.9% in the control group.
  • Common conditions like anemia and leukopenia appeared more frequently in co-infected patients, at rates of 58.8% and 16.3%, respectively.
  • Bilateral lung lesions and opportunistic infections were also more prevalent in those with HIV, highlighting the need for integrated treatment.

Cite This Study

Ivanes et al. (2025) studied this question.

synapsesocial.com/papers/68e70da790569dd607ee5b26https://doi.org/10.52645/mjhs.2025.3.19
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epidemiological and clinical analysis, and outcomes of tuberculosis co-infection among people living with HIV in Türkiye (2014–2024) ClinSurv HIV cohort: A large case series2025
  2. 2INVESTIGATING TB CO-INFECTION AMONG HIV PATIENTS: PREVALENCE AND ASSOCIATED CLINICAL AND BEHAVIORAL DETERMINANTS2025
  3. 3The role of combined opportunistic infections in the formation of fatal outcomes in patients with HIV-associated tuberculosis2025
  4. 4Adherence to treatment and medical and social characteristics of patients with pulmonary tuberculosis combined with HIV infection and chronic viral hepatitis2025
  5. 5A hospital-based observational study on HIV-TB co-infection2025