Review explores nanotechnology's role in enhancing drug delivery and targeting the tumor microenvironment, suggesting innovative strategies for cancer treatment.
Key Points
Nanotechnology enhances drug delivery precision, overcoming barriers posed by the tumor microenvironment.
ECM-degrading nanoparticles increase drug penetration, and immune-modulating nanoparticles shift macrophages towards an antitumor response.
Innovations like CAR T cells and pH-sensitive nanoparticles amplify therapeutic effects while minimizing side effects.
Clinical progress faces challenges such as ensuring nanoparticle biocompatibility and addressing diversity in patients' tumor microenvironments.