Carotid artery atherosclerosis, MRI-defined structural brain abnormalities, and cognitive performance in elderly American Indians: The Strong Heart Study
This study explores links between carotid atherosclerosis, brain abnormalities, and cognitive outcomes in American Indian adults, highlighting potential risks.
Key Points
Increased intima-media thickness correlates with greater brain atrophy, indicating risks to cognitive health.
Presence and extent of carotid plaque relate to poorer verbal fluency, supporting links between vascular health and cognition.
Longitudinal data from the Strong Heart Study informs potential interventions for cognitive health in underserved populations.
Adjustments for sociodemographic and clinical factors enhance the reliability of findings regarding brain health.