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October 8, 2025Current Opinion in Pediatrics

Early-life viral infections and asthma: new cells and ideas

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Authors

JLJie LanAMA. T. McCrayEBEmma Brown

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Overview

This review explores how early-life viral infections affect asthma development in pediatric populations, highlighting immunologic mechanisms and cell types involved.

Key Points

  • Asthma development is significantly influenced by early-life viral infections, raising clinical concerns.
  • Recent findings reveal that different immune cell types, such as granulocytes and CD4 + T-cells, contribute to asthmatic endotypes.
  • The review covers epidemiologic and immunologic insights connecting early-life infections to pediatric asthma.
  • Understanding pediatric asthma drivers extends beyond traditional immune pathways, indicating a need for updated therapeutic approaches.

Cite This Study

Lan et al. (2025) studied this question.

synapsesocial.com/papers/68e5c1b46950a706b22b4ee7https://doi.org/10.1097/mop.0000000000001514
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Also Consider

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  5. 5From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma2025