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October 7, 2025Bulgarian CardiologyOpen Access

Absolute and Functional Iron Deficiency in Heart Failure – Novel Definitions And Therapeutic Approach – Review of Literature

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Authors

GGGeorgi GoranovVGV. Goranova

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Overview

Literature review highlights new diagnostic criteria for iron deficiency in heart failure, indicating improved identification and treatment outcomes.

Key Points

  • Timely diagnosis of iron deficiency can improve treatment outcomes and reduce the risk of severe heart failure complications.
  • Proposed criteria set transferrin saturation below 20% as a key indicator, correlating significantly with survival and cardiovascular outcomes.
  • Review encompasses findings from multiple randomized clinical trials and meta-analyses supporting a need for redefining diagnostic criteria for iron deficiency.
  • Emerging indicators like serum soluble transferrin receptor add valuable insight into differentiating between absolute and functional iron deficiency.

Cite This Study

Goranov et al. (2025) studied this question.

synapsesocial.com/papers/68e585d0b1e78cc4e5f464cahttps://doi.org/10.3897/bgcardio.31.e150462
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