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October 7, 2025Intensive Care MedicineOpen Access

Determinants of ICU memories and the impact on the development and trajectory of post-traumatic stress symptoms: a multicenter longitudinal cohort study

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Authors

RKRens KookenBTBram TilburgsASArjen J. C. Slooter

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Overview

Longitudinal cohort study reveals connections between ICU memories and post-traumatic stress disorder symptoms, suggesting targeted interventions.

Key Points

  • Delusional memories are independently linked to PTSD symptoms, increasing significantly over time.
  • Female sex and prolonged deep sedation contribute to ICU amnesia, observed in nearly 14% of patients.
  • Delirium and extended ICU stay are associated with delusional memories, potentially worsening PTSD symptoms.
  • Targeted interventions during and post-ICU may help reduce the psychological impact of critical illness.

Cite This Study

Kooken et al. (2025) studied this question.

synapsesocial.com/papers/68e585d0b1e78cc4e5f463fdhttps://doi.org/10.1007/s00134-025-08132-4
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