Phytochemical Characterization And Nanosponge-Based Delivery Of Bioactives From Moringa Oleifera, Glycyrrhiza Glabra, And Ficus Religiosa

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This study demonstrates enhanced gastroprotective effects through a nanosponge delivery system, highlighting bioactives in herbal formulations.

The polyherbal nanosponge system showed prolonged release of bioactive compounds, leading to significant gastroprotective effects.
In rats, the treatment with nanosponge tablets reduced gastric ulcer index by approximately 50% compared to controls, indicating effective therapy.
Nanosponges encapsulated phytochemicals at high efficiencies (81–85%), producing stable nanosized particles for optimal delivery.
In vitro studies revealed a favorable extended release profile of about 77–83% of the active compounds over 24 hours, enhancing treatment outcomes.

Diwedi et al. (2025) studied this question.

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Authors

This study demonstrates enhanced gastroprotective effects through a nanosponge delivery system, highlighting bioactives in herbal formulations.

The polyherbal nanosponge system showed prolonged release of bioactive compounds, leading to significant gastroprotective effects.
In rats, the treatment with nanosponge tablets reduced gastric ulcer index by approximately 50% compared to controls, indicating effective therapy.
Nanosponges encapsulated phytochemicals at high efficiencies (81–85%), producing stable nanosized particles for optimal delivery.
In vitro studies revealed a favorable extended release profile of about 77–83% of the active compounds over 24 hours, enhancing treatment outcomes.

Diwedi et al. (2025) studied this question.

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