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October 5, 2025Neuro-OncologyOpen Access

P05.27.a Introduction of Whole Genome Sequencing as NHS Standard of Care for Glioma Patients in Two Neurosurgical Centres: West Midlands

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Authors

VWVictoria WykesEAErminia AlbaneseCBClare L. Bennett

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Overview

Observational analysis improved WGS turnaround time for glioma patients, suggesting enhanced precision medicine approaches in the NHS.

Key Points

  • WGS significantly reduced reporting time from 255 days to 137 days in glioma patients.
  • Out of 146 glioma samples, 26 patients had actionable molecular variants, leading to trial recommendations.
  • The most prevalent diagnosis was glioblastoma, comprising 64.8% of confirmed glioma cases.
  • Funding for a WGS coordinator is essential for continued success in implementing genomic medicine in the NHS.

Cite This Study

Wykes et al. (2025) studied this question.

synapsesocial.com/papers/68e24e6bd6d66a53c2473a14https://doi.org/10.1093/neuonc/noaf193.232
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