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October 5, 2025INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH

Use of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Opioids in the Treatment of Musculoskeletal Injuries in Athletes and Physical Activity Practitioners: Evidence and Risks Medications in Clinical Orthopedics

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Authors

DCDione Seabra de CarvalhoGGGustavo Gir GomesGYGiovana Casarini Yamashiro

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Overview

Cohort studies reveal the safety risks of NSAIDs and opioids in athletes, highlighting the need for careful use.

Key Points

  • NSAIDs effectively relieve acute pain and inflammation in injuries, but their long-term benefits remain unproven.
  • Significant risks of NSAIDs include gastrointestinal and cardiovascular issues, particularly threatening for athletes.
  • Efficacy of opioids in musculoskeletal injuries is limited to severe cases, posing substantial risks of dependence.
  • A rational, multifaceted treatment strategy prioritizing non-pharmacological therapies is essential for recovery.

Cite This Study

Carvalho et al. (2025) studied this question.

synapsesocial.com/papers/68e24e60d6d66a53c2473475https://doi.org/10.58806/ijhmr.2025.v4i8n03
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Relative Effectiveness of Physical Therapy and Pain Medication in Managing Sports-related Injuries2025
  2. 2The prevalence and perceptions of non-steroidal anti-inflammatory drug use among ultra-endurance runners2025 · 3 citations
  3. 3Intense control of pain for the treatment of sports injuries2025
  4. 4Pushing Limits – The role of pain and painkillers in Olympic Weightlifting2025
  5. 5Advances in Nonoperative Management of Osteoarthritis in Athletes2025