October 3, 2025Open Access

Cycling and tensed cells interpenetrated by non-cycling and compressed cells form a critical epithelial reticulum

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The study identifies a novel epithelial reticulum composed of cycling and compressed cells, highlighting regional balance in proliferation.
Surprising dynamics show that island growth of compressed cells conforms to a power-law distribution, indicating systematic properties.
Observational analysis explores how this epithelial reticulum self-organizes close to criticality without merging islands.
Findings may enable new perspectives on epithelial homeostasis, emphasizing its dynamic nature and subtle balance of forces.

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This research reveals a dynamic epithelial reticulum with cycling and compressed cells, suggesting a complex interplay in quiescent states.

Daraf et al. (2025) studied this question.

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This research reveals a dynamic epithelial reticulum with cycling and compressed cells, suggesting a complex interplay in quiescent states.