This review highlights how single-cell rna sequencing and spatial transcriptomics uncover tumor microenvironment complexities, suggesting new strategies for precision oncology.
Key Points
Integration of single-cell rna sequencing and spatial transcriptomics reveals tumor progression mechanisms and therapy resistance.
Emerging computational strategies enhance data integration, spotlighting immune evasion and fibroblast diversity in the tumor microenvironment.
The review identifies vital applications of integrated technologies in characterizing cellular communication networks within tumors.
Advancements in spatial multi-omics are set to improve precision oncology, emphasizing the importance of clinical implementation.