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October 3, 2025Frontiers in ImmunologyOpen Access

Role of novel protein acylation modifications in sepsis

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Authors

JWJing WangGanzhou People's HospitalAHAifeng HeLSLin SongShandong Provincial Hospital

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Implication

This review analyzes post-translational modifications involved in sepsis, highlighting their impact on protein function and disease outcomes.

Key Points

  • Novel lysine acylation modifications affect protein stability and activity, influencing sepsis progression significantly.
  • Comprehensive analysis reveals how seven specific post-translational modifications impact the pathogenesis of sepsis.
  • Advancements in mass spectrometry have uncovered these critical modifications, enhancing our understanding of sepsis.
  • Insights from this analysis could inform new diagnostic and therapeutic strategies for managing sepsis.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68e040eda99c246f578b326bhttps://doi.org/10.3389/fimmu.2025.1657194
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