October 3, 2025Clinical ChemistryOpen Access

A-098 Evaluation of an in-house cholinesterase assay for serum, plasma, and whole blood

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In-house cholinesterase assay demonstrates comparable performance to discontinued reagents in serum and plasma analysis.

The in-house cholinesterase assay exhibited comparable precision to discontinued commercial reagents, supporting its clinical application.
Method comparison analysis yielded high correlation (R=0.999) between the in-house assay and discontinued reagent for serum and plasma.
Linearity was confirmed with recovery ranges of 100.0-104.9% for serum, indicating reliable performance for varying analyte concentrations.
The assay's limit of detection was verified at 20 U/L, ensuring its sensitivity for clinical diagnostics.

Lü et al. (2025) studied this question.

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