October 3, 2025Clinical ChemistryOpen Access

A-352 Establishing pediatric reference intervals for thyroid function tests using the Hoffmann method in the Chinese population

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Pediatric RIs for thyroid function tests were established using the Hoffmann method with a focus on age-specific data.
Key findings showed that thyroid hormones vary by age, necessitating tailored reference intervals for accurate diagnosis.
Data collection involved thyroid function tests from children in multiple age groups, with methods including outlier removal and Box-Cox transformation.
The results indicate that indirect methods can effectively establish pediatric reference intervals, essential for detecting thyroid disorders.

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This study establishes pediatric RIs for thyroid function tests using Hoffmann method, highlighting age-specific variations in thyroid hormones.

Danni Mu (2025) studied this question.

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This study establishes pediatric RIs for thyroid function tests using Hoffmann method, highlighting age-specific variations in thyroid hormones.