October 3, 2025Clinical ChemistryOpen Access

B-065 Evaluation of the Relationship Between H-Index- and Hemoglobin-Normalized Glucose-6-Phosphate Dehydrogenase and Pyruvate Kinase Activities

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Strong agreement was observed between estimated Hb and measured Hb concentrations for both G6PD and PK activities.
The normalization of enzyme activities to the H-index demonstrated comparable precision with normalization to measured Hb in multiple samples.
G6PD and PK activities normalized to estimated Hb were equivalent to those normalized to measured Hb, indicating reliability of the H-index.
The findings imply that H-index can serve as an effective surrogate for Hb, enhancing laboratory testing efficiency.

Authors

MUM. Chinonye UdechukwuARUP Laboratories (United States)KDKelly DoyleAbbVie (United States)

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Implication

Observational analysis shows strong agreement between estimated and measured Hb in G6PD and PK testing, suggesting H-index normalization may streamline evaluations.

Cite This Study

Udechukwu et al. (2025) studied this question.

synapsesocial.com/papers/68e040e5a99c246f578b2f7e https://doi.org/10.1093/clinchem/hvaf086.463

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Implication

Observational analysis shows strong agreement between estimated and measured Hb in G6PD and PK testing, suggesting H-index normalization may streamline evaluations.

B-065 Evaluation of the Relationship Between H-Index- and Hemoglobin-Normalized Glucose-6-Phosphate Dehydrogenase and Pyruvate Kinase Activities

Key Points

Discussion

Implication

Cite This Study

B-065 Evaluation of the Relationship Between H-Index- and Hemoglobin-Normalized Glucose-6-Phosphate Dehydrogenase and Pyruvate Kinase Activities

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider