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October 3, 2025Onderstepoort Journal of Veterinary Research

Resistance, virulence and genetic diversity of Salmonella Typhimurium in South Africa (1999–2021)

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Authors

NMNkagiseng MoatsheESEmmanuel SeakamelaKMKhanyisile R. Mbatha

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Overview

This assessment reveals high antibiotic resistance and virulence genes in Salmonella Typhimurium isolates in South Africa, suggesting urgent public health strategies.

Key Points

  • High antibiotic resistance was found in Salmonella Typhimurium, with 86.8% resistant to ciprofloxacin and 69.0% to ceftriaxone.
  • The study identified prevalent virulence genes, with 100% of isolates containing invA, highlighting potential public health threats.
  • Genetic analysis also revealed multiple plasmids, with the most common being 90 kb detected in 71.3% of isolates.
  • Multidrug resistance was observed, with isolates showing resistance to up to 11 different antibiotics, emphasizing the need for surveillance.

Cite This Study

Moatshe et al. (2025) studied this question.

synapsesocial.com/papers/68e02f3cf0e39f13e7fa25d5https://doi.org/10.4102/ojvr.v92i1.2217
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