Review discusses diagnostic criteria and treatment options in hemophagocytic lymphohistiocytosis, highlighting its clinical challenges and implications.
Key Points
Earlier identification of hemophagocytic lymphohistiocytosis can improve outcomes and reduce mortality.
New laboratory findings, such as serum cytokines CXCL9 and IL-18, aid in the diagnosis of HLH.
Hemophagocytic lymphohistiocytosis occurs with severe inflammation and immune overactivation, making timely diagnosis critical.
Recognition of HLH in healthy individuals responding to infections emphasizes the need for prompt treatment initiation.