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October 3, 2025Annals of Clinical Microbiology and AntimicrobialsOpen Access

Biocide, antifungal susceptibility and virulence characteristics of Clade 1 Candidozyma auris strains

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Authors

AKAyşe KalkancıSESidre ErganişEŞElif Ayça Şahin

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Overview

Study reveals antifungal resistance and virulence factors in Clade 1 C. auris strains, suggesting links to biocide tolerance.

Key Points

  • Thirty-one percent of Clade 1 C. auris isolates exhibited fluconazole resistance, highlighting antifungal resistance challenges.
  • Correlations were found between amphotericin B and triclosan MICs, indicating possible links between antifungal resistance and biocide tolerance.
  • Identification of virulence factors like biofilm formation was observed in all isolates, suggesting enhanced infection risk.
  • Further molecular investigation is required to fully understand the resistance mechanisms and virulence pathways in C. auris.

Cite This Study

Kalkancı et al. (2025) studied this question.

synapsesocial.com/papers/68e02f2cf0e39f13e7fa2018https://doi.org/10.1186/s12941-025-00821-8
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