Efficacy and safety of remimazolam for induction and maintenance of general anesthesia in day surgery: a randomized controlled non-inferiority clinical trial
Randomized controlled trial assesses remimazolam's safety and efficacy in general anesthesia, indicating it compares favorably to propofol in short surgeries.
Key Points
Efficacy of remimazolam and propofol for general anesthesia was 100%, showcasing strong performance in day surgeries.
Significant differences were observed in time to loss of consciousness, with propofol outperforming remimazolam (P < 0.01).
The analysis revealed propofol group had lower heart rate and mean arterial pressure at induction compared to remimazolam (P < 0.05).
The use of remimazolam showed non-inferiority to propofol, with no increase in adverse reactions during recovery.