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October 3, 2025Biological and Clinical Sciences Research JournalOpen Access

Normal Pressure Hydrocephalus in the Elderly: A Narrative Review of Diagnostic Complexity, Biomarker Potential, and Surgical Outcomes

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Authors

ASAli Akbar ShahRSRiyaz ShahEKErum Khatoon

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Overview

Narrative review reveals diagnostic challenges and potential biomarkers in normal pressure hydrocephalus, highlighting outcomes from treatment in elderly populations.

Key Points

  • Normal pressure hydrocephalus often leads to underdiagnosis in older adults with overlapping dementia symptoms, and raising awareness is crucial.
  • Ventriculoperitoneal shunting can improve gait performance significantly, while cognitive and urinary outcomes vary among patients.
  • Cerebrospinal fluid dynamics are vital in understanding normal pressure hydrocephalus, with neuroimaging techniques aiding in diagnosis.
  • Cultural perceptions in low- and middle-income countries contribute to the misrecognition of symptoms as normal aging, complicating treatment.

Cite This Study

Shah et al. (2025) studied this question.

synapsesocial.com/papers/68e02f2cf0e39f13e7fa1eeehttps://doi.org/10.54112/bcsrj.v6i9.1977
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidental Diagnosis of Normal Pressure Hydrocephalus in Elderly Patients Presenting With Acute Neurological Illnesses: A Report of Two Cases2025
  2. 2From the past to the present: evolving theories in the pathophysiology of normal pressure hydrocephalus2025
  3. 3Early Presentation and Management of Normal Pressure Hydrocephalus in a Middle-Aged Patient: A Case Report2025
  4. 4Normal pressure hydrocephalus: current concepts in diagnosis and management focused on clinical decision2025
  5. 5Cerebral Blood Flow, Autoregulation and Vascular Reactivity in Normal Pressure Hydrocephalus: a systematic review2025