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October 2, 2025MedicineOpen Access

Integrative analysis of Zidan Yinxie capsules for psoriasis treatment: Insights from network pharmacology, molecular dynamics simulation, and GEO database analysis

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Authors

JBJiachen BuCMChen‐Xue MaoLNLisheng Nan

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Overview

Integrative analysis reveals Zidan Yinxie capsules may improve psoriasis through active ingredients and immune targets.

Key Points

  • Zidan Yinxie capsules demonstrate therapeutic potential in psoriasis by interacting with key immune targets.
  • A total of 189 active ingredients and 227 targets were identified, with 148 genes linked to inflammation.
  • Network pharmacology and molecular dynamics were employed to validate the interactions between compounds and proteins.
  • Key findings suggest STAT3 and ESR1 are pivotal in psoriasis treatment, indicating future research paths.

Cite This Study

Bu et al. (2025) studied this question.

synapsesocial.com/papers/68de796d5b556a9128e1acachttps://doi.org/10.1097/md.0000000000044446
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