This research demonstrates the development and optimization of a melissa officinalis nanoemulgel using design of experiments, suggesting its role in anti-inflammatory therapies.
Key Points
The optimized melissa officinalis nanoemulgel showed a droplet size of 127.31 nm and good colloidal stability.
FTIR analysis confirmed the presence of functional groups, supporting the oil's therapeutic potential derived from melissa officinalis.
In vivo tests using a carrageenan-induced rat paw model demonstrated significant edema reduction, highlighting the nanoemulgel's anti-inflammatory effects.
Inhibition of staphylococcus aureus and escherichia coli was observed, suggesting potential antibacterial properties of the melissa nanoemulgel.