This observational study reveals GDM alters gut microbiome in mothers and their infants, suggesting potential long-term health implications.
Key Points
Infants of mothers with GDM exhibited distinct gut microbiomes compared to those of healthy mothers, indicating developmental disparities.
Statistical analysis showed significant changes in the microbiome profiles of mothers with GDM, specifically linked to insulin resistance and inflammation.
Bacterial members associated with GDM, such as Blautia and Collinsella, were identified in infant stool samples suggesting a vertical transmission of dysbiosis.
Understanding GDM's influence on early gut microbiome colonization could highlight risks for future metabolic diseases in affected infants.