October 2, 2025Cancer InformaticsOpen Access

Systematic Analysis of CA9 as a Pan-Cancer Marker for Prognosis and Immunity

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CA9 was significantly upregulated in 29 out of 33 cancer types, indicating a strong potential as a pan-cancer marker.
Elevated CA9 expression correlated with poor overall survival and progression-free interval in numerous cancers, including GBM and LUAD.
The associations of CA9 with immune cell infiltration suggest its relevance in understanding tumor immunity and treatment response.
Systematic bioinformatics approaches utilized extensive datasets to analyze CA9's role across diverse cancer types, highlighting its broad implications.

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Systematic analysis reveals CA9's prognostic value in various cancer types, implying significant implications for immunotherapy.

Yi et al. (2025) studied this question.

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