Gianotti-Crosti syndrome associated with measles, mumps and rubella vaccination in an infant – A case report

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Gianotti-Crosti syndrome was observed in an 11-month-old infant after MMR vaccination, indicating a potential vaccine-related reaction.
The infant developed a pruritic, symmetrical papular rash that resolved completely within 3 weeks, demonstrating the benign nature of GCS.
Management involved conservative care with topical emollients and oral antihistamines, confirming a non-complicated outcome.
Recognising post-vaccination GCS is crucial to prevent unnecessary investigations and offer reassurance to caregivers.

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A case report reveals Gianotti-Crosti syndrome following MMR vaccination in an infant, highlighting its benign nature.

Priyadarshini et al. (2025) studied this question.

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